The nature of the hemorrhagic disorder accompanying hemolytic transfusion reactions in man.

By JULIUS R. KREVANS, DUDLEY P. JACKSON, C. LOCKARD CONLEY AND ROBERT C. HARTMANN H E tIOLYTIC TRANSFUSION REACTIONS nitty be associated with the developnsemst of a serious hemorrhagic temidemicy. As early as 1919, Drimsker amid Brittinghamm reported the occurrence of umsexplained bleedimsg followimig the tramssfusioms of serologically imscompatible red blood cells, amid since thets a few’ similar instances have been reported.2m4 The sudden onset of umiexplaimsed bleeditsg may be the first sigms of a hemolytic transfusiomi reactioms, especially it-i patients utider getseral amiesthesia. Relatively few observatiomis have beets recorded as to the nature of this hensorrhagic disorder. In sonic of the recently reported cases, hypofibrimiogetsemia,t2’ m3